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“With an RNA vaccine, it’s very easy to switch,” says Drew Weissman, an immunologist at the University of Pennsylvania whose early research helped make mRNA vaccines possible. The vaccines contain the genetic instructions for cells in the body to make the spike protein, the part of the virus that invades human cells, helping trigger an immune response so the body is ready to respond if it encounters the actual virus. (Other vaccines, like the one from Johnson & Johnson that is likely to be approved soon, would also be fairly simple to update, though the process would take a few more steps—and thus more time—than the new shots that use mRNA.) … [Read more...] about How easy will it be to update the COVID vaccine if the virus mutates too much?

Who wore what The other members of the First and Second families wore American designers. Both President Biden and Second Gentleman Doug Emhoff wore classic Ralph Lauren suits. First Lady Jill Biden wore an ocean blue wool, tweed and velvet coat, along with a matching dress from Makarian, a four-year-old label from American designer Alexandra O’Neill. Notably many of the women at the inauguration—including Kamala Harris, Jill Biden, and Michelle Obama—were dressed from head to toe in the same color, possibly to symbolize community and unity. … [Read more...] about Decoding the fashion at Biden’s inauguration

Signal Boosting Like South by Soutwest, its distant relative in Austin, Upstream isn’t just about seeing shows but bolstering the region’s music economy—think of what places like New York, Nashville, and Los Angeles mean to the music business, but with a tech twist. During the festival’s two days, an event space at the stadium hosted Seattle-linked keynote speakers—Macklemore, Quincy Jones, Kill Rock Stars president Portia Sabin, film composer Ron Jones, Mike McCready of Pearl Jam—while a slew of panels featured entrepreneurs, technologists, and musicians talking about everything from data analytics to video game composition. Part of the aim was to underscore existing untapped networking opportunities for Seattle’s artists and techies. “Hopefully we can start creating those relationships and really start building our music economy,” says Vetting. … [Read more...] about A Tech Billionaire Tries to Reboot The “Best Music Scene In The World”