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Hugel logo Letybo, Hugel’s botulinum toxin product, won marketing approval from health regulators in France, the company said Thursday. The green light came on Jan. 27, just two days after Hugel received an approval recommendation from the Heads of Medicines Agencies (HMA), a network of the heads of national authorities whose organizations are responsible for the regulation of medical products for human and veterinary use in the European economic area. European Medicines Agency is an active member of the HMA. Hugel said it is very rare for a European country to give the permission so quickly as it normally takes about one to three months to approve a new drug after a HMA recommendation. France will be the first European country that Letybo is exported to. Hugel aims to enter a total of 11 countries including Britain, Germany, Spain and Italy within the first quarter. China granted sale approval for Letybo in October 2020. It is currently waiting for marketing approvals for … [Read more...] about Hugel’s botulinum toxin product wins marketing approval in France

Share to Twitter Share to Linkedin Global car sales were supposed to rally this year as manufacturers dragged themselves out of the coronavirus mire, but a combination of Russia’s invasion of Ukraine, China’s renewed medical emergency shutdown and key component shortages mean a more than 5% contraction is likely, according to a report from Germany’s Center for Automotive Research (CAR AR ). The report said it’s not all bad news for manufacturers. Underlying demand is still strong, and component shortages mean a lack of new vehicles are reaching buyers and prices are strong, generating what amounts to windfall profits. Second-hand vehicles are also in demand. You can forget radar cruise control or plug-in hybrids; availability is the most important feature. CAR said global sales in 2022 will fall to 67.6 million from last year’s 71.3 million. Sales were thought to have bottomed out in 2020 at 68.6 million after diving from 79.9 million in 2019 because … [Read more...] about Global Car Sales To Fall, Spooked By Russian Invasion, China’s Shutdown

Share to Twitter Share to Linkedin Much of last week was spent in Rome, which is overwhelming in its sights, though the highlight for me was the peace of the Appian Way. Rome is also rich in lessons on civilisation, politics and strategy – many of which appear to be lost on leaders today. In that respect it is a good place to consider the rise and fall of nations, a phenomenon that is gathering pace. More broadly if we consider the biggest, most powerful cities in the history of the world, Rome stands out. Many of these great cities— Babylon, Nimrud (south of Mosul), and Alexandria—were the focal points of great civilizations but, sadly, have been in the news for the wrong reasons. It is surprising how many Chinese cities have been “the biggest” through time, with cities like Nanjing, Xi’an, Hangzhou, and Beijing dominating the period from AD 600 to AD 1800. London briefly took over during the nineteenth century, and the biggest-city baton was then passed to … [Read more...] about Is China In Decline?

Hugel logo [HUGEL] Hugel's Letybo botulinum toxin product was approved for sale in Britain, the company said Thursday. After a green light from the Medicines & Healthcare products Regulatory Agency, Hugel will start selling the product in the second quarter. Britain will be the third European country that Letybo is exported to. It gained approvals from France and Austria in February. Hugel wants to sell to 11 countries in the first half of the year. Britain has the largest botulinum toxin market in Europe. The five countries with the biggest markets — Britain, France, Germany, Italy and Spain — control 70 percent of Europe's botulinum toxin market. The size of Britain's botulinum toxin market is estimated at about 120 billion won this year, according to Hugel. That figure is expected to increase to 150 billion won by the end of 2025. About 7 to 10 percent of the population in Britain have used some kind of botulinum toxin products. "The approval from Britain will be a … [Read more...] about Hugel can sell its botulinum toxin product in U.K.

A general view shows the oil refinery of the Lukoil company in Volgograd, Russia April 22, 2022. Picture taken with a drone. (REUTERS) BRUSSELS — The European Union could combine import tariffs on Russian oil with the phased oil embargo it is trying to put in place to shrink Russia’s energy revenues, US Treasury Secretary Janet Yellen said on Tuesday. The tariff concept will be presented at a G7 finance leaders’ meeting this week as an economically less costly way to siphon away oil revenues from Moscow while producing faster results, US Treasury officials told reporters. The tariff plan would aim to keep more Russian oil in the global market, limiting price spikes spurred by a full embargo, while limiting the amount of money Russia can earn from exports, the officials said. The European Commission, the EU’s executive body, has proposed an embargo on imports of Russian crude that would start to phase in next year in response to Moscow’s war in Ukraine, but some eastern … [Read more...] about EU could combine tariffs on Russian oil with embargo – Yellen

London (CNN Business) Europe can't make up its mind on how to pay for Russia natural gas imports that continue to fuel homes, businesses and power stations. The confusion centers on the logistics of the payments themselves. Several European gas buyers have been preparing to work around the Kremlin's demand that gas bills be paid in rubles, rather than the euros or dollars stipulated in contracts. According to Russia's new payment mechanism, buyers in "unfriendly" countries must open two accounts at Gazprombank — one in euros and the second in rubles, from which payments for the gas would be made. But on Tuesday, the European Commission said companies opening an account in Russia's Gazprombank to allow their payments to be converted into rubles would fall foul of EU sanctions. That statement appeared to contradict guidance the Commission gave just four days earlier, which led some of Europe's biggest energy companies to assume they could get … [Read more...] about Europe is still confused about how to pay its Russian gas bills

Share to Twitter Share to Linkedin We have fresh data from Forrester’s Q2 B2C Marketing CMO Pulse Survey, 2022 — a cross-industry survey among 153 US B2C marketing executives, VP and above, at brands with at least 500 employees. We provided a list of 13 trending marketing priorities and asked respondents to indicate the degree to which each is a priority (critical, high, moderate, low, or “not on their agenda”) for their marketing department during the remainder of 2022. The results are in, and the top five priorities that were rated “critical” most often are: 1. Focus On Employer Branding And The Employee Experience Acquiring and retaining high-performing talent is incredibly challenging right now, making it front and center to the CEO’s agenda. And CMOs have an important role to play as employer branding is increasingly powered by marketing. Why? Because traditional brand strategy is the bedrock of employer brand strategy. This requires emboldened CMOs … [Read more...] about Top 5 Most Critical CMO Priorities For B2C Brands

SK Biopharmaceuticals' logo SK Biopharmaceuticals went into the red in the first quarter, reporting 35 billion won ($27 million) in net losses compared to a 129 billion won net profit in the same period a year earlier. The losses were larger than the market expectation. The consensus was 26.6 billion won of net losses, according to FnGuide. The Pangyo, Gyeonggi-based biopharmaceutical company blamed accounting reasons as the biggest factor behind the losses as the company booked $110 million for milestone payments and another 50.4 billion won for selling its 12 percent stake in Arvelle Therapeutics in the first quarter of last year. Quarterly revenue fell 71 percent to 41.1 billion won, while operating loss stood at 37.1 billion won. Both figures fell short of expectations as the market consensus of revenue was 49.2 billion won with 26.8 billion won of operating loss. "The U.S. sales of Cenobamate have been growing, which will likely grow more in the second quarter as … [Read more...] about SK Biopharmaceuticals reports $27 million in net losses in Q1

Share to Twitter Share to Linkedin Every legendary investor worth their salt has some sort of phrase to describe what investors should be doing right this very minute. “Be fearful when others are greedy, be greedy when others are fearful.” “Buy when there’s blood in the streets.” Largely speaking, most stocks on the market are on sale to some extent. And sure, we could go out and make a few targeted bets on these bargains. But I’d prefer to squeeze even more value out of the stock market. Enter closed-end funds (CEFs). Why CEFs Are Our Best Option Now If we were to go out and buy an exchange-traded fund (ETF) that invests in, say, the Nasdaq Composite or Russell 2000, or really any area of the market you felt was underpriced, you’d be able to enjoy in the collective discounts of all their holdings. No more, no less. But with CEFs , we can do even better. My mom, to this day, refuses to pay the sticker price. If there’s a … [Read more...] about This 9.2% Monthly Dividend Portfolio Is In The Bargain Bin

The 75th Cannes Film Festival, opening ceremony and screening of the film “Coupez” (Final Cut) out of competition, Cannes, France, May 17, 2022. Julianne Moore arrives on stage with Vincent Lindon, jury president. Image: Reuters/Sarah Meyssonnier CANNES, France — The Cannes Film Festival rolled out the red carpet Tuesday as the Mediterranean port city filled up with cinema stars, festival-goers and oglers for the 75th anniversary event, bringing buzz and glamour back to the resort destination. “I’m simply overjoyed,” the festival’s jury president Vincent Lindon told a packed press conference, flanked by jury members: actors and filmmakers including Rebecca Hall, Noomi Rapace, Deepika Padukone, Jeff Nichols and Asghar Farhadi. The world’s biggest film festival runs from May 17 to 28, back to its traditional calendar following two years of pandemic disruptions, and marking the return of parties and high hopes from the industry that it will spark the return of audiences to movie … [Read more...] about Cannes Film Festival rolls out red carpet as crowds descend for 75th anniversary